Lipid droplets are essential intracellular organelles responsible for energy storage. Metabolic abnormalities in lipid droplets are closely linked to major diseases such as obesity and fatty liver disease. Traditional lipid droplet probes can only report on their morphology and location but offer no insight into their internal lipid composition. Bio-Vision...
10
May
10
May
Fluorescent reporter groups are the foundation of fluorescent probe development. Their performance directly determines the detection sensitivity and practicality of the probe. Bio-Vision Technology, in collaboration with Professor Qin Wang, introduces an important fluorescein derivative—3-Methoxyfluorescein – leveraging its unique optical properties to empower high-sensitivity detection research. Outstanding Performance Ultra-Low Background, High...
28
Apr
Challenges and Demands in Fluorescent Microsphere Encoding Technology Fluorescent microsphere flow analysis is a technology that uses fluorescently labeled microspheres for rapid, quantitative analysis in flow cytometry, enabling simultaneous measurement of fluorescence signals from multiple samples to obtain characteristic information about cells or particles. Current preparation methods involve adsorbing fluorescent...
23
Apr
Global HCV Burden and Detection Challenges Over 170 million people worldwide are infected with the Hepatitis C Virus (HCV), a single-stranded positive-sense RNA virus. Chronic infection often leads to severe liver diseases, including chronic hepatitis, cirrhosis, and liver cancer. Currently, the most common HCV detection methods—fluorescence quantitative PCR and ELISA—are...
14
Apr
Colloidal gold (also known as gold nanoparticles) refers to a dispersion of gold nanoparticles (diameter 1–100 nm) in a solvent, typically water. Due to its excellent stability, biocompatibility, and unique optical and electromagnetic properties, colloidal gold has become a key material in fields such as in vitro diagnostics, biosensing, cancer...
01
Apr
In 2016, Professor Xuechuan Hong at Wuhan University published a paper in Nature Materials [1], reporting the first successful synthesis of a metabolizable near-infrared II (NIR-II) small-molecule dye—CH1055—capable of labeling various biomolecules. With a maximum emission wavelength in the range of 1000–1600 nm, CH1055 exhibits excellent biocompatibility, clearance properties, and imaging sensitivity....
