NH2-Pluronic F127-NH2 (Pluronic Diamine) is a biomedical polymeric material derived from the modification of Pluronic triblock copolymer (composed of polyethylene oxide and polypropylene oxide) through the introduction of amine groups. It features a moderate molecular weight, combining good water solubility, amphiphilicity, and reactive activity. The material exhibits excellent biocompatibility, is degradable in vivo, and yields harmless degradation products.
In drug delivery, it can form micelles to encapsulate hydrophobic drugs, prolonging their circulation time in the bloodstream. The amine groups also allow conjugation with targeting molecules for precise transport. In tissue engineering, it can be fabricated into three-dimensional porous scaffolds to support cell growth, and can be blended with other biomaterials (such as collagen) to create a favorable microenvironment for tissue regeneration.
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Huang Yugang Professor at the School of Pharmaceutical Sciences, Guangzhou Medical University. |
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He has long been dedicated to research on polymeric carriers for nucleic acid drug delivery, focusing on the design and application of functional carriers to advance nucleic acid therapeutics. |
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| With over 30 SCI publications as first or corresponding author, 3 authorized invention patents, and leadership in projects such as the NSFC Young Scientists Fund and industry collaborations, he consistently promotes industry-academia integration and the translation of research outcomes. | |
Product Advantages:
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F127 is an FDA-approved material, ensuring safety.
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Drug carriers prepared from F127 exhibit thermosensitivity, enabling temperature-controlled drug release.
Notice for Bulk/Industrial Orders
J&K Scientific stably supplies NH2-Pluronic F127-NH2, a collaborative product with Professor Yugang Huang of Guangzhou Medical University.
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- #Cat:9430740 NH2-Pluronic F127-NH2, 95%
艳 李
