Colloidal gold (also known as gold nanoparticles) refers to a dispersion of gold nanoparticles (diameter 1–100 nm) in a solvent, typically water. Due to its excellent stability, biocompatibility, and unique optical and electromagnetic properties, colloidal gold has become a key material in fields such as in vitro diagnostics, biosensing, cancer therapy, and medical imaging.
Key Advantages of Colloidal Gold
a. Easy Conjugation
Forms stable Au-S bonds, enabling convenient conjugation with various antibodies, antigens, proteins, oligonucleotides, drugs, polymers, and other molecules for targeted delivery and highly specific detection.
b. Signal Enhancement Effect
Exhibits a typical localized surface plasmon resonance (LSPR) effect. Under specific wavelength illumination, a strong electromagnetic field is generated at specific sites, significantly enhancing Raman signals and improving detection sensitivity.
c. High X-ray Scattering Capability
Gold has a higher atomic number (Au 79 vs I 53) and X-ray absorption coefficient (at 100 keV: Au 5.16 cm²·g⁻¹, I 1.94 cm²·g⁻¹). The contrast effect per unit mass of gold is approximately 2.7 times that of iodine, making it ideal for high-contrast CT imaging.
Wide Range of Applications
-
In vitro diagnostics (pregnancy tests, Mycobacterium tuberculosis, influenza virus, tumor markers, etc.)
-
Food and agricultural product testing
-
Biosensing
-
Tumor photothermal therapy and radiotherapy sensitization
-
CT imaging
-
Surface-enhanced Raman spectroscopy (SERS)
BioDragon × Prof. Lingjie Meng: Research Commercialization
We offer ultra-high concentration colloidal gold developed and commercialized by Professor Lingjie Meng’s research group, featuring the following outstanding advantages:
-
Tunable particle size: from 45 nm to 70 nm
-
High uniformity: irregularly shaped particles < 5%, stable upon storage
-
Ultra-high concentration: up to 5 mg/mL (100 OD), surfactant-free
-
Ready to use: can be directly diluted or labeled, reducing loss of antigens/antibodies/proteins, and significantly improving experimental reproducibility
Ideal for high-sensitivity diagnostics, precision labeling, and research or industrial applications requiring high concentrations.
|
Related Products
Ultra-high concentration colloidal gold, 99%, 45nm, 5mg/ml, dispersed in water, no surfactant Cat:984391 CAS:7440-57-5
Ultra-high concentration colloidal gold, 99%, 50nm, 5mg/ml, dispersed in water, no surfactant Cat:929422 CAS:7440-57-5
Ultra-high concentration colloidal gold, 99%, 60nm, 5mg/ml, dispersed in water, no surfactant Cat:916070 CAS:7440-57-5
Ultra-high concentration colloidal gold, 99%, 70nm, 5mg/ml, dispersed in water, no surfactant Cat:927671 CAS:7440-57-5
Need Bulk Quantities? Let’s Talk Strategy.
Contact our technical sales team today for a fast, formal quotation tailored to your project requirements.
艳 李
