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(S)-4,4-Difluoropyrrolidine-2-carboxylic acid|CS-W021174|52683-81-5

(S)-4,4-Difluoropyrrolidine-2-carboxylic acid

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Sku TS246CS-W021174_25_G
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Product Information

Product Name
(S)-4,4-Difluoropyrrolidine-2-carboxylic acid
Brand Name
ChemScene
Product Number
CS-W021174
CAS
52683-81-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
15216102
IUPAC Name
(2S)-4,4-difluoropyrrolidine-2-carboxylic acid
InChI Key
ZPBIYZHGBPBZCK-VKHMYHEASA-N
SMILES
C1C@H(NCC1(F)F)C(=O)O

References Data Source From Pubchem

Advances in the chemical synthesis of human proteoforms
Publication Name: Science China. Life sciences
Publication Date: 2025-04-08
DOI: 10.1007/s11427-024-2860-5

Structure-activity study of oncocin: On-resin guanidinylation and incorporation of homoarginine, 4-hydroxyproline or 4,4-difluoroproline residues
Publication Name: Bioorganic Chemistry
Publication Date: 2023-12
DOI: 10.1016/j.bioorg.2023.106876

Protein Design with Fluoroprolines: 4,4‐Difluoroproline Does Not Eliminate the Rate‐Limiting Step of Thioredoxin Folding
Publication Name: Chembiochem : a European journal of chemical biology
Publication Date: 2021-10-08
DOI: 10.1002/cbic.202100418

Biodistribution, pharmacokinetics, dosimetry of [68Ga]Ga-DOTA.SA.FAPi, and the head-to-head comparison with [18F]F-FDG PET/CT in patients with various cancers
Publication Name: European Journal of Nuclear Medicine and Molecular Imaging
Publication Date: 2020-11-26
DOI: 10.1007/s00259-020-05132-y

Cyclic derivatives of morphiceptin possess anti-transit effect in the gastrointestinal tract and alleviate abdominal pain in mice
Publication Name: Pharmacological reports : PR
Publication Date: 2020-03-03
DOI: 10.1007/s43440-020-00084-4