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2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one|CS-W006058|120014-07-5

2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

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Sku TS246CS-W006058_1_G
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Product Information

Product Name
2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
Brand Name
ChemScene
Product Number
CS-W006058
CAS
120014-07-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
10762160
IUPAC Name
(2E)-2-(1-benzylpiperidin-4-yl)methylidene-5,6-dimethoxy-3H-inden-1-one
InChI Key
LPMOTUSFDTTWJL-UDWIEESQSA-N
SMILES
COC1=C(C=C2C(=C1)C/C(=C\C3CCN(CC3)CC4=CC=CC=C4)/C2=O)OC

References Data Source From Pubchem

Cholinesterase as a Target for Drug Development in Alzheimer’s Disease
Publication Name: Targeting Enzymes for Pharmaceutical Development
Publication Date: 2020
DOI: 10.1007/978-1-0716-0163-1_18

Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease
Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2018-10-05
DOI: 10.1016/j.ejmech.2018.09.031

Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid analogues
Publication Name: Journal of Enzyme Inhibition and Medicinal Chemistry
Publication Date: 2018-01-01
DOI: 10.1080/14756366.2018.1458030

Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil
Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2017-02-15
DOI: 10.1016/j.ejmech.2016.10.036

Design, Synthesis, and Evaluation of Donepezil-Like Compounds as AChE and BACE-1 Inhibitors
Publication Name: ACS Medicinal Chemistry Letters
Publication Date: 2016-03-30
DOI: 10.1021/acsmedchemlett.5b00483