N-Hydroxymethyl succinimide|CS-0217538|5146-68-9

N-Hydroxymethyl succinimide

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Sku TS246CS-0217538_1_G
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Product Information

Product Name
N-Hydroxymethyl succinimide
Brand Name
ChemScene
Product Number
CS-0217538
CAS
5146-68-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
95286
IUPAC Name
1-(hydroxymethyl)pyrrolidine-2,5-dione
InChI Key
AZVYYSCOCHRFKW-UHFFFAOYSA-N
SMILES
C1CC(=O)N(C1=O)CO

References

Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening
Publication Name: SLAS discovery : advancing life sciences R & D
Publication Date: 2020-01
DOI: 10.1177/2472555219873068

A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein
Publication Name: Molecular Pharmacology
Publication Date: 2019-11
DOI: 10.1124/mol.119.115964

Synthesis, Biological Evaluation and Pharmacokinetic Studies of Mefenamic Acid - N-Hydroxymethylsuccinimide Ester Prodrug as Safer NSAID
Publication Name: Medicinal chemistry (Shariqah (United Arab Emirates))
Publication Date: 2016-07-29
DOI: 10.2174/1573406412666160107113548

Novel ibuprofen prodrugs with improved pharmacokinetics and non-ulcerogenic potential
Publication Name: Medicinal Chemistry Research
Publication Date: 2013-06-11
DOI: 10.1007/s00044-013-0639-8

Influence of N-hydroxymethyl-p-isopropoxyphenylsuccinimide on the anticonvulsant action of different classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model
Publication Name: Epilepsy Research
Publication Date: 2012-06
DOI: 10.1016/j.eplepsyres.2012.01.003