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Product Information

Product Name
3-3,5-Bis(trifluoromethyl)phenylamino-4-(1R,2R)-2-(1-piperidinyl)cyclohexylamino-3-cyclobutene-1,2-dione, 98%
Brand Name
US-Strem
Product Number
07-5610
CAS
1211565-11-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
46217045
IUPAC Name
3-3,5-bis(trifluoromethyl)anilino-4-(1R,2R)-2-piperidin-1-ylcyclohexylaminocyclobut-3-ene-1,2-dione
InChI Key
XUZPZFXQOUOXFH-IAGOWNOFSA-N
SMILES
C1CCN(CC1)C@@H2CCCCC@H2NC3=C(C(=O)C3=O)NC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F

Application

Technical Notes:
1. a-Hydrazination: Catalytic enantiosele ctive a-hydrazination of 1 ,3-dicarbonyl compounds with
azodicarboxylates was investigated in the presence of our newly developed hydrogen bonding catalyst.
2.Michael Addition: Asymmetric organocatalytic 1 ,4-additions provide access to a large number of
biologically relevant compounds.
References:
1.Org. Lett., 2010, 12, 2028-2031.
2.Org. Biomol. Chem., 2013. 11, 7 705-7711.

References

Recent Advances on Benzofuranones: Synthesis and Transformation via C–H Functionalization

Publication Name: Synthesis
Publication Date: 2021-03-31
DOI: 10.1055/a-1405-5761

Kinetic Resolution of 5-Substituted Oxazinones with Bifunctional Chiral Base/Squaramide Organocatalysts

Publication Name: Synlett
Publication Date: 2017-05-31
DOI: 10.1055/s-0036-1588852

Recent Advances in Catalytic Asymmetric Reactions of o-Quinone Methides

Publication Name: Synthesis
Publication Date: 2015-10-21
DOI: 10.1055/s-0035-1560356|10.1055/s-0035-1560370