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Sku CI37874_1_G
Chem Impex
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Product Information

Product Name
Fludarabine
Brand Name
Chem Impex
Product Number
37874
CAS
21679-14-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
657237
IUPAC Name
(2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI Key
HBUBKKRHXORPQB-FJFJXFQQSA-N
SMILES
C1=NC2=C(N=C(N=C2N1C@H3C@H(C@@H(C@H(O3)CO)O)O)F)N

Description

Fludarabine is widely utilized in research focused on:

Cancer Treatment: Primarily used in the treatment of chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma, Fludarabine is effective in targeting and inhibiting the growth of cancerous cells.

Immunosuppressive Therapy: It is employed in preparing patients for stem cell transplants by suppressing the immune system, thereby reducing the risk of transplant rejection.

Combination Chemotherapy: Fludarabine is often combined with other chemotherapeutic agents to enhance efficacy against various hematological malignancies, providing a synergistic effect that can improve patient outcomes.

Research in Molecular Biology: Used as a tool in laboratory studies, it helps researchers understand the mechanisms of DNA synthesis and repair, contributing to advancements in cancer biology.

Clinical Trials: Fludarabine is frequently involved in clinical trials aimed at exploring new treatment regimens for blood cancers, offering hope for improved therapies and patient care.