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Sku CI35191_5_G
Chem Impex
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Product Information

Product Name
Fmoc-L-alanine methyl ester
Brand Name
Chem Impex
Product Number
35191
CAS
146346-88-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11834337
IUPAC Name
methyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate
InChI Key
NLYFFHNUTFDXLO-LBPRGKRZSA-N
SMILES
CC@@H(C(=O)OC)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Description

Fmoc-L-alanine methyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of the Fmoc protecting group, which is crucial for selective deprotection during the synthesis process.

Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, providing a versatile framework for modifying biological activity and improving drug efficacy.

Bioconjugation: The compound is employed in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in developing targeted therapies and diagnostics.

Research in Protein Engineering: It aids in the design of novel proteins with enhanced properties, allowing researchers to explore new functionalities and applications in biotechnology.

Analytical Chemistry: Fmoc-L-alanine methyl ester is used in various analytical methods, including chromatography, to separate and identify amino acids and peptides, providing valuable insights into complex mixtures.

References Data Source From Pubchem

Methane Sulphonic Anhydride Enabled an Efficient and Straightforward Protocol for the Synthesis of Hydroxamic Acid Derivatives and Evaluation of their In-silico ADME Properties

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2026-01-17
DOI: 10.1007/s10989-025-10800-4

Model studies on protease-catalysed peptide synthesis using 9-fluorenylmethoxycarbonyl protected amino acid derivatives

Publication Name: Monatshefte für Chemie / Chemical Monthly
Publication Date: 1992-11
DOI: 10.1007/bf00810932