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Sku CI32630_25_MG
Chem Impex
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Product Information

Product Name
H-Pro-Arg-AMC·2HCl
Brand Name
Chem Impex
Product Number
32630
CAS
546103-85-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
23349541
IUPAC Name
N-5-(diaminomethylideneamino)-1-(4-methyl-2-oxochromen-7-yl)amino-1-oxopentan-2-ylpyrrolidine-2-carboxamide
InChI Key
YZJVBUAIFJVLAS-UHFFFAOYSA-N
SMILES
CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C3CCCN3

Description

H-Pro-Arg-AMC·2HCl is widely utilized in research focused on:

Biochemical Assays: This compound serves as a substrate in enzyme assays, particularly for proteases. Its ability to release a fluorescent signal upon cleavage makes it invaluable for real-time monitoring of enzyme activity.

Drug Development: In pharmaceutical research, it is used to study the mechanisms of action of various drugs, particularly those targeting proteolytic pathways, aiding in the design of more effective therapeutics.

Cellular Studies: Researchers employ this compound to investigate cellular processes involving protein degradation and synthesis, providing insights into diseases related to protein misfolding.

Diagnostic Tools: Its unique properties allow it to be integrated into diagnostic assays, enhancing the detection of specific biomarkers in clinical samples, which is crucial for early disease diagnosis.

Academic Research: It is frequently used in academic settings for teaching and research purposes, helping students and researchers understand complex biochemical interactions and enzyme kinetics.