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Sku CI32471_1_G
Chem Impex
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Product Information

Product Name
7-Ethyl-10-hydroxycamptothecin
Brand Name
Chem Impex
Product Number
32471
CAS
86639-52-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
104842
IUPAC Name
(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo11.8.0.02,11.04,9.015,20henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
InChI Key
FJHBVJOVLFPMQE-QFIPXVFZSA-N
SMILES
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C@@4(CC)O)C2=NC5=C1C=C(C=C5)O

Description

7-Ethyl-10-hydroxycamptothecin is widely utilized in research focused on:

Cancer Treatment: This compound is being investigated for its potential as an anti-cancer agent, particularly in treating various types of tumors. Its ability to inhibit DNA topoisomerase I makes it a promising candidate in oncology.

Pharmaceutical Development: Researchers are exploring its formulation in drug delivery systems, enhancing the bioavailability of cancer therapies. This could lead to more effective treatments with fewer side effects.

Combination Therapies: It is being studied in combination with other chemotherapeutic agents to improve treatment efficacy and reduce drug resistance in cancer cells.

Biological Research: The compound serves as a valuable tool in cellular and molecular biology studies, helping scientists understand the mechanisms of cancer cell proliferation and apoptosis.

Natural Product Synthesis: Its structure inspires synthetic chemists to develop new analogs with improved therapeutic profiles, potentially leading to novel cancer treatments.