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Sku CI31352_100_G
Chem Impex
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Product Information

Product Name
4-(tert-Butyldimethylsilyl)oxy-1-butanol
Brand Name
Chem Impex
Product Number
31352
CAS
87184-99-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
186403
IUPAC Name
4-tert-butyl(dimethyl)silyloxybutan-1-ol
InChI Key
IJEMXJANZPVITP-UHFFFAOYSA-N
SMILES
CC(C)(C)Si(C)(C)OCCCCO

Application

4-(tert-Butyldimethylsilyl)oxy-1-butanol is widely utilized in research focused on:

Organic Synthesis: This compound serves as a versatile protecting group for alcohols in organic synthesis, allowing chemists to selectively modify other functional groups without interference.

Pharmaceutical Development: It plays a crucial role in the synthesis of complex pharmaceutical compounds, enhancing the stability and solubility of active ingredients in drug formulations.

Material Science: Used in the development of siloxane-based materials, it contributes to the creation of polymers with improved thermal and mechanical properties, ideal for coatings and adhesives.

Analytical Chemistry: This chemical is employed in chromatography techniques, aiding in the separation and analysis of various compounds, which is essential for quality control in laboratories.

Biotechnology: It is utilized in the preparation of biosensors and other biotechnological applications, enhancing the sensitivity and specificity of detection methods.

References

Stereoselective 1,4-Addition of Primary Alcohols to γ-Alkoxy-α,β-unsaturated Esters

Publication Name: Synthesis
Publication Date: 2020-09-22
DOI: 10.1055/s-0040-1707274

Total Synthesis of δ-Sanshool and Analogues Thereof

Publication Name: Synthesis
Publication Date: 2016-03-16
DOI: 10.1055/s-0035-1561580

Total Synthesis of the Nonenolide Xyolide Using a Regioselective Nucleophilic Epoxide Opening Approach

Publication Name: Synthesis
Publication Date: 2015-06-19
DOI: 10.1055/s-0034-1380780

Darunavir

Publication Name: Pharmaceutical Substances
Publication Date: 2010

Stereoselective Synthesis of the C(53)–C(67) Polyene Fragment of Amphidinol 3

Publication Name: Synlett
Publication Date: 2007-09
DOI: 10.1055/s-2007-985601