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Product Information

Product Name
N-Boc-imidazole
Brand Name
Chem Impex
Product Number
31296
CAS
49761-82-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
521262
IUPAC Name
tert-butyl imidazole-1-carboxylate
InChI Key
MTBKGWHHOBJMHJ-UHFFFAOYSA-N
SMILES
CC(C)(C)OC(=O)N1C=CN=C1

Application

N-Boc-imidazole is widely utilized in research focused on:

Synthetic Chemistry: It serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, allowing researchers to create complex molecules efficiently.

Drug Development: The compound is used in the development of new drugs, particularly in creating imidazole-containing compounds that exhibit biological activity, such as antifungal and anticancer properties.

Bioconjugation: N-Boc-imidazole is employed in bioconjugation techniques, aiding in the attachment of biomolecules to surfaces or other molecules, which is crucial in developing targeted therapies and diagnostics.

Material Science: It finds applications in the production of functional materials, such as polymers and coatings, enhancing properties like durability and chemical resistance.

Research Reagents: The compound is a valuable reagent in various laboratory experiments, facilitating reactions that require protection of amine groups, thus improving yields and selectivity.

References Data Source From Pubchem

The First Example of Palladium(II)-Catalyzed Oxidative C–N Cross Coupling of 2H-Imidazole 1-Oxide with Azoles

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 2019-08-22
DOI: 10.1007/s10593-019-02536-z

Advances in Transition Metal-Catalyzed Asymmetric Hydrogenation of Heteroaromatic Compounds

Publication Name: Stereoselective Formation of Amines
Publication Date: 2013
DOI: 10.1007/128_2013_480

tert-Butyl imidazole-1-carboxylate

Publication Name: Acta crystallographica. Section E, Structure reports online
Publication Date: 2009-01-28
DOI: 10.1107/s1600536809003110

CCDC 722127: Experimental Crystal Structure Determination

Publication Date: 2009
DOI: 10.5517/ccs7ffv

1,1,1,3,3,3-Hexafluoroisopropanol: A Recyclable Organocatalyst forN-Boc Protection of Amines

Publication Name: Synthesis
Publication Date: 2008-09-05
DOI: 10.1055/s-2008-1067272