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Sku CI31031_100_MG
Chem Impex
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Product Information

Product Name
Rapamycin from Streptomyces hygroscopicus
Brand Name
Chem Impex
Product Number
31031
CAS
53123-88-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
5284616
IUPAC Name
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-(2R)-1-(1S,3R,4R)-4-hydroxy-3-methoxycyclohexylpropan-2-yl-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo30.3.1.04,9hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
InChI Key
QFJCIRLUMZQUOT-HPLJOQBZSA-N
SMILES
CC@@H1CCC@H2CC@@H(/C(=C/C=C/C=C/C@H(CC@H(C(=O)C@@H(C@@H(/C(=C/C@H(C(=O)CC@H(OC(=O)C@@H3CCCCN3C(=O)C(=O)C@@1(O2)O)C@H(C)CC@@H4CCC@H(C@@H(C4)OC)O)C)/C)O)OC)C)C)/C)OC

Description

Rapamycin from Streptomyces hygroscopicus is widely utilized in research focused on:

Immunosuppression: Commonly used in organ transplantation, it helps prevent rejection by suppressing the immune response, allowing for better graft survival.

Cancer Treatment: Its ability to inhibit cell growth makes it valuable in oncology, particularly for certain types of tumors, providing a targeted approach to cancer therapy.

Cardiovascular Health: Research indicates that it may help in treating conditions like atherosclerosis by inhibiting vascular smooth muscle cell proliferation.

Anti-Aging Research: Studies suggest it may extend lifespan in various organisms, making it a focus in gerontology for potential applications in age-related diseases.

Drug Development: Used as a model compound in pharmaceutical research, it aids in the development of new drugs that target similar pathways, enhancing therapeutic options.