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Sku CI30404_5_MG
Chem Impex
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Product Information

Product Name
Triptolide
Brand Name
Chem Impex
Product Number
30404
CAS
38748-32-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
107985
IUPAC Name
(1S,2S,4S,5S,7R,8R,9S,11S,13S)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo11.7.0.02,4.02,9.05,7.09,11.014,18icos-14(18)-en-17-one
InChI Key
DFBIRQPKNDILPW-CIVMWXNOSA-N
SMILES
CC(C)C@@12C@@H(O1)C@H3C@@4(O3)C@5(CCC6=C(C@@H5CC@H7C@4(C@@H2O)O7)COC6=O)C

Description

Triptolide is widely utilized in research focused on:

Cancer Treatment: Triptolide has shown promising anti-cancer properties, particularly in inhibiting the growth of various cancer cell lines. Its ability to induce apoptosis (programmed cell death) makes it a candidate for developing new cancer therapies.

Anti-Inflammatory Applications: This compound is effective in reducing inflammation, which can benefit conditions like rheumatoid arthritis and other inflammatory diseases. Its use in formulations can help manage pain and swelling.

Neuroprotective Effects: Research indicates that triptolide may protect neuronal cells from damage, offering potential applications in treating neurodegenerative diseases such as Alzheimer's and Parkinson's.

Immunosuppressive Properties: Triptolide is used in transplant medicine to prevent organ rejection by suppressing the immune response, making it valuable for patients undergoing organ transplants.

Natural Pesticide: In agriculture, triptolide has been explored as a natural pesticide due to its ability to disrupt the life cycle of certain pests, providing an eco-friendly alternative to synthetic chemicals.