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Sku CI30002_5_G
Chem Impex
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Product Information

Product Name
Sodium deoxycholate
Brand Name
Chem Impex
Product Number
30002
CAS
302-95-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
23668196
IUPAC Name
sodium (4R)-4-(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopentaaphenanthren-17-ylpentanoate
InChI Key
FHHPUSMSKHSNKW-SMOYURAASA-M
SMILES
CC@H(CCC(=O)O-)C@H1CCC@@H2C@@1(C@H(CC@H3C@H2CCC@H4C@@3(CCC@H(C4)O)C)O)C.Na+

Application

Sodium deoxycholate is widely utilized in research focused on:

Cell Membrane Studies: This compound is often used to solubilize membrane proteins, making it easier for researchers to study their structure and function. Its ability to disrupt lipid bilayers is crucial for understanding cellular processes.

Drug Delivery Systems: Sodium deoxycholate serves as an effective emulsifier in pharmaceutical formulations, enhancing the bioavailability of poorly soluble drugs. This is particularly beneficial in the development of oral and injectable medications.

Biotechnology Applications: In the production of vaccines and therapeutic proteins, it aids in the purification processes by removing contaminants, thus improving yield and quality.

Analytical Chemistry: It is used in various assays and chromatographic techniques, helping to improve the resolution and sensitivity of detection methods for biomolecules.

Cosmetic Formulations: Sodium deoxycholate is incorporated into skincare products for its emulsifying properties, allowing for better texture and stability in creams and lotions.

References

The molecular basis of lamin-specific chromatin interactions

Publication Name: Nature Structural & Molecular Biology
Publication Date: 2025-08-01
DOI: 10.1038/s41594-025-01622-5

Advances in BRAF mutated colorectal cancer-could deoxycholic acid be the culprit?

Publication Name: Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Publication Date: 2025-07
DOI: 10.1016/j.bbcan.2025.189347

Evidence for the involvement of secondary bile acids on peripheral and central regulation of feed intake in rainbow trout

Publication Name: American journal of physiology. Endocrinology and metabolism
Publication Date: 2025-06-01
DOI: 10.1152/ajpendo.00072.2025

Directed Evolution of Transcriptional Factor BreR for Improved Substrate Specificity Toward Deoxycholic Acid and Ursodeoxycholic Acid

Publication Name: Biotechnology Journal
Publication Date: 2025-06
DOI: 10.1002/biot.70058