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Sku CI29903_100_MG
Chem Impex
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Product Information

Product Name
Actinomycin D
Brand Name
Chem Impex
Product Number
29903
CAS
50-76-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
457193
IUPAC Name
2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo14.3.0nonadecan-6-ylphenoxazine-1,9-dicarboxamide
InChI Key
RJURFGZVJUQBHK-IIXSONLDSA-N
SMILES
CC@@H1C@@H(C(=O)NC@@H(C(=O)N2CCCC@H2C(=O)N(CC(=O)N(C@H(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC@H6C@H(OC(=O)C@@H(N(C(=O)CN(C(=O)C@@H7CCCN7C(=O)C@H(NC6=O)C(C)C)C)C)C(C)C)C)N)C

Description

Actinomycin D is widely utilized in research focused on:

Cancer Treatment: This compound is a potent chemotherapeutic agent used to treat various cancers, including Wilms' tumor and rhabdomyosarcoma, by inhibiting DNA transcription.

Cell Biology Studies: Researchers use Actinomycin D to study gene expression and cellular responses, as it effectively blocks RNA synthesis, allowing scientists to investigate the role of specific genes.

Antibiotic Research: Actinomycin D has applications in microbiology as it exhibits antibiotic properties, helping researchers explore new antimicrobial therapies against resistant strains.

Development of Anticancer Drugs: The compound serves as a lead structure in the design of new anticancer agents, providing insights into structure-activity relationships that can enhance drug efficacy.

Biochemical Research: It is frequently used in studies involving protein synthesis and cellular metabolism, allowing scientists to dissect complex biological pathways and mechanisms.