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Sku CI28090_5_G
Chem Impex
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Product Information

Product Name
3-(Trifluoromethyl)phenylboronic acid
Brand Name
Chem Impex
Product Number
28090
CAS
1423-26-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2734388
IUPAC Name
3-(trifluoromethyl)phenylboronic acid
InChI Key
WOAORAPRPVIATR-UHFFFAOYSA-N
SMILES
B(C1=CC(=CC=C1)C(F)(F)F)(O)O

Description

3-(Trifluoromethyl)phenylboronic acid is widely utilized in research focused on:

Organic Synthesis: This compound serves as a key building block in the synthesis of various organic molecules, particularly in the development of pharmaceuticals and agrochemicals.

Chemical Reactions: It is commonly used in Suzuki-Miyaura cross-coupling reactions, which are essential for forming carbon-carbon bonds in complex organic compounds.

Material Science: The compound is applied in the development of advanced materials, including polymers and coatings, enhancing properties such as thermal stability and chemical resistance.

Bioconjugation: It plays a significant role in bioconjugation strategies, allowing researchers to attach biomolecules to surfaces or other compounds, facilitating drug delivery and diagnostic applications.

Fluorinated Compounds: The trifluoromethyl group enhances the biological activity and lipophilicity of compounds, making it valuable in medicinal chemistry for improving drug efficacy.

References Data Source From Pubchem

Solid dosing in High-Throughput Experimentation: generalization of mass enhancer technologies for submilligram scale

Publication Name: Journal of Flow Chemistry
Publication Date: 2024-01-09
DOI: 10.1007/s41981-023-00304-x

Solid-State Suzuki–Miyaura Cross-Coupling Reaction Using Mechanochemistry

Publication Name: Palladium-Catalyzed Mechanochemical Cross-Coupling Reactions
Publication Date: 2024
DOI: 10.1007/978-981-97-1991-4_3

Mechanochemical Monoarylation of Dihaloarenes Enabled by In-Situ Crystallization

Publication Name: Palladium-Catalyzed Mechanochemical Cross-Coupling Reactions
Publication Date: 2024
DOI: 10.1007/978-981-97-1991-4_7

Oxidative Esterification of Aldehydes

Publication Name: Science of Synthesis
Publication Date: 2024