Product Added to Cart!
$43.70

FREE
SHIPPING

100% MONEY
BACK GUARANTEE

ONLINE
SUPPORT 24/7

Available on backorder. No lead time available. Please request a quote.
Sku CI27703_1_G
Chem Impex
Get Bulk Quote

Product Information

Product Name
Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate
Brand Name
Chem Impex
Product Number
27703
CAS
149771-09-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2737153
IUPAC Name
ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate
InChI Key
OUACXMUEZBQRBJ-UHFFFAOYSA-N
SMILES
CCOC(=O)C1=CN=C(N=C1C(F)(F)F)N

Description

Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders, due to its unique trifluoromethyl group which enhances bioactivity.

Agricultural Chemistry: It is used in the formulation of agrochemicals, providing effective solutions for pest control and crop protection, thereby improving agricultural productivity.

Material Science: The compound is explored for its potential in developing advanced materials, particularly in coatings and polymers, where its properties can enhance durability and resistance to environmental factors.

Biochemical Research: Researchers utilize this chemical in studies related to enzyme inhibition and receptor binding, contributing to a better understanding of biological processes and disease mechanisms.

Fluorinated Compound Synthesis: Its ability to introduce trifluoromethyl groups makes it valuable in synthesizing other fluorinated compounds, which are important in various industrial applications, including pharmaceuticals and specialty chemicals.

References Data Source From Pubchem

Design and synthesis of 2-amino-4-(trifluoromethyl)pyrimidine derivatives as potential Werner-dependent antiproliferative agents

Publication Name: Molecular Diversity
Publication Date: 2025-06-15
DOI: 10.1007/s11030-025-11225-3

Chan–Lam–Evans Coupling is Now Available on Carbon Nanotubes

Publication Name: Synfacts
Publication Date: 2019-04-15
DOI: 10.1055/s-0037-1612491

Reaction of 2-(ethoxymethylidene)-3-oxo carboxylic acid esters with tetrazol-5-amine

Publication Name: Russian Journal of Organic Chemistry
Publication Date: 2015-07
DOI: 10.1134/s1070428015070179

Comparisons of pKa and log P values of some carboxylic and phosphonic acids: Synthesis and measurement

Publication Name: The AAPS Journal
Publication Date: 2001-06-01
DOI: 10.1208/ps030210