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Sku CI26254_250_MG
Chem Impex
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Product Information

Product Name
5-Nitrothiazole
Brand Name
Chem Impex
Product Number
26254
CAS
14527-46-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
541661
IUPAC Name
5-nitro-1,3-thiazole
InChI Key
VVVCJCRUFSIVHI-UHFFFAOYSA-N
SMILES
C1=C(SC=N1)N+(=O)O-

Description

5-Nitrothiazole is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of antimicrobial agents. Its unique structure allows for the modification of drug properties, enhancing efficacy against resistant strains.

Agricultural Chemicals: It is used in the formulation of pesticides and herbicides, providing effective solutions for crop protection. Its ability to target specific pests makes it a valuable component in sustainable agriculture.

Material Science: 5-Nitrothiazole is employed in the creation of specialty polymers and coatings, which offer improved durability and resistance to environmental factors. This application is crucial for industries requiring long-lasting materials.

Analytical Chemistry: The compound is utilized as a reagent in various analytical techniques, including spectrophotometry and chromatography. Its effectiveness in detecting trace amounts of other substances makes it essential for quality control in laboratories.

Biochemical Research: It plays a role in studying enzyme inhibition and metabolic pathways, aiding researchers in understanding disease mechanisms and developing targeted therapies.

References Data Source From Pubchem

Regioselective Nitration of (2E)-3-Aryl-2-(4-arylthiazol-2-yl)acrylonitriles

Publication Name: Russian Journal of General Chemistry
Publication Date: 2024-10
DOI: 10.1134/s1070363224100025

Anthelmintic efficacy of nitazoxanide in dogs naturally infected with Toxocara canis

Publication Name: Parasitology Research
Publication Date: 2024-03-16
DOI: 10.1007/s00436-024-08168-3

Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT

Publication Name: Bioorganic Chemistry
Publication Date: 2023-10
DOI: 10.1016/j.bioorg.2023.106676

Synthesis and antiplasmodial assessment of nitazoxanide and analogs as new antimalarial candidates

Publication Name: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents
Publication Date: 2022-01-28
DOI: 10.1007/s00044-021-02843-1

Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease

Publication Name: Current Research in Chemical Biology
Publication Date: 2022
DOI: 10.1016/j.crchbi.2022.100025