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Sku CI25937_25_G
Chem Impex
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Product Information

Product Name
5-Chloro-2-mercaptobenzoxazole
Brand Name
Chem Impex
Product Number
25937
CAS
22876-19-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
708870
IUPAC Name
5-chloro-3H-1,3-benzoxazole-2-thione
InChI Key
BOBIZYYFYLLRAH-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1Cl)NC(=S)O2

Description

5-Chloro-2-mercaptobenzoxazole is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in developing anti-inflammatory and antimicrobial agents.

Agricultural Chemicals: It is used in formulating pesticides and fungicides, providing effective protection against a range of plant pathogens, thereby enhancing crop yield.

Analytical Chemistry: The compound is employed in analytical methods for detecting heavy metals and other contaminants in environmental samples, ensuring compliance with safety regulations.

Material Science: It is utilized in the production of specialty polymers and coatings that offer enhanced durability and resistance to environmental degradation.

Biochemical Research: Researchers use this compound to study enzyme inhibition and receptor interactions, contributing to a better understanding of biological processes and disease mechanisms.

References Data Source From Pubchem

Discovery of selective fragment-sized immunoproteasome inhibitors

Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2021-07-05
DOI: 10.1016/j.ejmech.2021.113455

Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9

Publication Name: Angewandte Chemie (International ed. in English)
Publication Date: 2016-05-04
DOI: 10.1002/anie.201511351

Design, synthesis, docking, and biological evaluation of some novel 5-chloro-2-substituted sulfanylbenzoxazole derivatives as anticonvulsant agents

Publication Name: Medicinal Chemistry Research
Publication Date: 2014-07-03
DOI: 10.1007/s00044-014-1111-0

Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)

Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2013-12-15
DOI: 10.1016/j.bmc.2013.10.037

Synthesis of Suvorexant

Publication Name: Synfacts
Publication Date: 2011-07-20
DOI: 10.1055/s-0030-1260673