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Sku CI25756_1_G
Chem Impex
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Product Information

Product Name
2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine
Brand Name
Chem Impex
Product Number
25756
CAS
1513-69-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
135418580
IUPAC Name
2-amino-4-(trifluoromethyl)-1H-pyrimidin-6-one
InChI Key
ZEPSVMLZBXDPGU-UHFFFAOYSA-N
SMILES
C1=C(N=C(NC1=O)N)C(F)(F)F

Application

2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting viral infections and cancer therapies.

Agricultural Chemicals: It is used in the formulation of agrochemicals, enhancing the efficacy of herbicides and fungicides, which helps in improving crop yields.

Biochemical Research: Researchers employ this chemical in studies related to enzyme inhibition and metabolic pathways, aiding in the understanding of cellular processes.

Material Science: The compound is explored for its potential in developing advanced materials, including polymers and coatings that require specific thermal and chemical resistance.

Fluorine Chemistry: Its unique trifluoromethyl group makes it valuable in fluorine chemistry, allowing for the creation of novel compounds with enhanced properties for various applications.

References

Synthesis of Novel Amide-Functionalized Imidazo[1,2-a]pyrimidin-5(1H)-ones and Their Biological Evaluation as Anticancer Agents

Publication Name: Russian Journal of Organic Chemistry
Publication Date: 2022-03
DOI: 10.1134/s1070428022030216

Simulation of IR and Raman spectral based on scaled DFT force fields: A case study of 2-amino 4-hydroxy 6-trifluoromethylpyrimidine, with emphasis on band assignment

Publication Name: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Publication Date: 2008-11-15
DOI: 10.1016/j.saa.2007.12.033