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Sku CI25745_25_G
Chem Impex
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Product Information

Product Name
4-Oxo-4-(2-thienyl)butyric acid
Brand Name
Chem Impex
Product Number
25745
CAS
4653-08-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
78385
IUPAC Name
4-oxo-4-thiophen-2-ylbutanoic acid
InChI Key
ULJMYWHLMLRYSO-UHFFFAOYSA-N
SMILES
C1=CSC(=C1)C(=O)CCC(=O)O

Application

4-Oxo-4-(2-thienyl)butyric acid is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in creating anti-inflammatory and analgesic agents.

Organic Synthesis: It is employed in organic chemistry for the development of novel compounds, leveraging its unique thiophene structure to enhance reactivity and selectivity in reactions.

Material Science: The compound is used in the formulation of advanced materials, including polymers and coatings, where its properties can improve durability and chemical resistance.

Agricultural Chemistry: It finds applications in the development of agrochemicals, contributing to the formulation of effective herbicides and pesticides that are environmentally friendly.

Biochemical Research: Researchers utilize this compound to study metabolic pathways and enzyme interactions, providing insights into biological processes and potential therapeutic targets.

References

Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2019-10-30
DOI: 10.1021/acs.jmedchem.9b00988

Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A

Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2019-01-01
DOI: 10.1016/j.ejmech.2018.10.027

Direction of 3-bromothiophene acylation with succinyl chloride

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 2013-06-21
DOI: 10.1007/s10593-013-1258-5

High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors

Publication Name: Antiviral Research
Publication Date: 2011-09
DOI: 10.1016/j.antiviral.2011.06.006

Peculiarities of the behavior of succinyl dichloride in Friedel-Crafts reaction with thiophenes*

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 2011-01
DOI: 10.1007/s10593-011-0653-z