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Sku CI24901_5_G
Chem Impex
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Product Information

Product Name
2-Amino-6-(trifluoromethyl)benzothiazole
Brand Name
Chem Impex
Product Number
24901
CAS
777-12-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2735955
IUPAC Name
6-(trifluoromethyl)-1,3-benzothiazol-2-amine
InChI Key
WEDYEBJLWMPPOK-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1C(F)(F)F)SC(=N2)N

Description

2-Amino-6-(trifluoromethyl)benzothiazole is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders, enhancing drug efficacy.

Agricultural Chemicals: It is used in the formulation of agrochemicals, providing effective solutions for pest control while minimizing environmental impact compared to traditional pesticides.

Material Science: The compound is incorporated into polymers and coatings, improving their thermal stability and chemical resistance, which is crucial for high-performance applications.

Analytical Chemistry: It acts as a reagent in analytical methods, aiding in the detection and quantification of specific compounds, thus streamlining laboratory processes.

Fluorescent Probes: This chemical is employed in the development of fluorescent probes for biological imaging, allowing researchers to visualize cellular processes with high precision.

References Data Source From Pubchem

Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels

Publication Name: ACS Medicinal Chemistry Letters
Publication Date: 2023-06-23
DOI: 10.1021/acsmedchemlett.3c00224

Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography

Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2014-04-15
DOI: 10.1016/j.bmc.2014.03.001

2-Aminobenzothiazole derivatives: Search for new antifungal agents

Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2013-06
DOI: 10.1016/j.ejmech.2013.03.064

Effective killing of the human pathogen Candida albicans by a specific inhibitor of non‐essential mitotic kinesin Kip1p

Publication Name: Molecular Microbiology
Publication Date: 2007-06-15
DOI: 10.1111/j.1365-2958.2007.05787.x

Riluzole Series. Synthesis and in Vivo “Antiglutamate” Activity of 6-Substituted-2-benzothiazolamines and 3-Substituted-2-imino-benzothiazolines

Publication Name: Journal of Medicinal Chemistry
Publication Date: 1999-07-01
DOI: 10.1021/jm980202u