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Chem Impex
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Product Information

Product Name
tert-Butyl 3-formyl-1H-indole-1-carboxylate
Brand Name
Chem Impex
Product Number
24144
CAS
57476-50-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2764519
IUPAC Name
tert-butyl 3-formylindole-1-carboxylate
InChI Key
GDYHUGFAKMUUQL-UHFFFAOYSA-N
SMILES
CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)C=O

Application

tert-Butyl 3-formyl-1H-indole-1-carboxylate is widely utilized in research focused on:

Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly those targeting neurological disorders, enhancing drug development efficiency.

Organic Synthesis: It is employed in organic synthesis reactions, particularly for creating complex indole derivatives, which are valuable in medicinal chemistry.

Biological Research: Researchers use this compound to study its biological activity, including its potential anti-cancer properties, contributing to the development of new therapeutic agents.

Material Science: It finds applications in the development of advanced materials, such as polymers and coatings, due to its unique chemical structure and reactivity.

Fluorescent Probes: The compound is utilized in creating fluorescent probes for bioimaging, allowing for better visualization of biological processes in live cells.

References

Pyrrolobenzodiazepines: natural sources, therapeutic uses, and future in neurological treatments

Publication Name: Medicinal Chemistry Research
Publication Date: 2023-12-18
DOI: 10.1007/s00044-023-03177-w

Catalyst-Free Electrochemical C-3 Formylation of Indoles in an Aqueous Biphasic System

Publication Name: Synfacts
Publication Date: 2021-08-18
DOI: 10.1055/s-0040-1720824

First in class (S,E)-11-[2-(arylmethylene)hydrazono]-PBD analogs as selective CB2 modulators targeting neurodegenerative disorders

Publication Name: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents
Publication Date: 2020-10-04
DOI: 10.1007/s00044-020-02640-2

Utilization of 1H-Indole-3-carboxaldehyde as a Precursor for the Synthesis of Bioactive Indole Alkaloids

Publication Name: Synthesis
Publication Date: 2018-10-15
DOI: 10.1055/s-0037-1610288

From 3-(1H-Indol-3-yl)prop-2-enone O-Methyl Oximes

Publication Name: Science of Synthesis
Publication Date: 2018