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Sku CI23244_25_G
Chem Impex
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Product Information

Product Name
2-Chloroquinoline-4-carboxylic acid
Brand Name
Chem Impex
Product Number
23244
CAS
5467-57-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
230582
IUPAC Name
2-chloroquinoline-4-carboxylic acid
InChI Key
ICNCOMYUODLTAI-UHFFFAOYSA-N
SMILES
C1=CC=C2C(=C1)C(=CC(=N2)Cl)C(=O)O

Application

2-Chloroquinoline-4-carboxylic acid is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly those targeting infectious diseases, due to its ability to enhance bioactivity.

Agricultural Chemistry: It is used in the formulation of agrochemicals, providing effective solutions for pest control and crop protection, which is crucial for sustainable agriculture.

Material Science: The compound is incorporated into the development of novel materials, such as polymers and coatings, which exhibit improved chemical resistance and durability.

Analytical Chemistry: It acts as a reagent in analytical methods, helping researchers to detect and quantify other substances in complex mixtures, thereby facilitating quality control in various industries.

Biochemical Research: This chemical is utilized in studies related to enzyme inhibition and receptor binding, contributing to the understanding of biological processes and the development of new therapeutic strategies.

References Data Source From Pubchem

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2023-10-30
DOI: 10.1016/j.bbrc.2023.08.050

Synthesis of Quinoline-2-Carboxylic Acid Aryl Ester and Its Apoptotic Action on PC3 Prostate Cancer Cell Line

Publication Name: Applied Biochemistry and Biotechnology
Publication Date: 2022-11-29
DOI: 10.1007/s12010-022-04258-z

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

Publication Name: The Journal of biological chemistry
Publication Date: 2022-08
DOI: 10.1016/j.jbc.2022.102228

Synthesis and Biological Activity of Quinoline-2-Carboxylic Acid Aryl Esters and Amides

Publication Name: Pharmaceutical Chemistry Journal
Publication Date: 2017-08
DOI: 10.1007/s11094-017-1613-4

Synthesis and Antiinflammatory Activity of Isonicotinic and Cinchoninic Acid Derivatives

Publication Name: Pharmaceutical Chemistry Journal
Publication Date: 2002-08
DOI: 10.1023/a:1021258510259