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Sku CI22871_1_G
Chem Impex
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Product Information

Product Name
Neotetrazolium Chloride
Brand Name
Chem Impex
Product Number
22871
CAS
298-95-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2723605
IUPAC Name
2-4-4-(3,5-diphenyltetrazol-2-ium-2-yl)phenylphenyl-3,5-diphenyltetrazol-2-ium dichloride
InChI Key
WYFYSTBFFDOVJW-UHFFFAOYSA-L
SMILES
C1=CC=C(C=C1)C2=NN(N+(=N2)C3=CC=C(C=C3)C4=CC=C(C=C4)N+5=NC(=NN5C6=CC=CC=C6)C7=CC=CC=C7)C8=CC=CC=C8.Cl-.Cl-

Application

Neotetrazolium Chloride is widely utilized in research focused on:

Cell Viability Assays: This compound is commonly used in laboratories to assess cell viability and proliferation. It helps researchers determine the effects of drugs or treatments on cell health, making it essential in pharmacological studies.

Biochemical Research: Neotetrazolium Chloride serves as a redox indicator in various biochemical assays. Its ability to change color in response to redox reactions allows scientists to monitor metabolic activity in cells.

Microbial Activity Testing: In microbiology, this chemical is employed to evaluate the metabolic activity of microorganisms. It aids in assessing the effectiveness of antimicrobial agents, which is crucial for developing new antibiotics.

Histology and Pathology: This compound is used in tissue staining procedures, helping pathologists visualize cellular structures under a microscope. Its application enhances the accuracy of diagnoses in medical laboratories.

Environmental Testing: Neotetrazolium Chloride is applied in assessing soil and water quality by measuring microbial activity. This is vital for environmental scientists monitoring ecosystem health and pollution levels.

References Data Source From Pubchem

The interaction of imidazole-, imidazolium-, and tetrazolium-containing compounds with DNA

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2013-03-01
DOI: 10.1016/j.bmcl.2012.11.106

Anti-Plasmodium activity of tetrazolium salts

Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2008-02-15
DOI: 10.1016/j.bmc.2007.11.005

New antifungals selected by molecular topology

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 1998-09-22
DOI: 10.1016/s0960-894x(98)00460-0