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Sku CI22820_250_G
Chem Impex
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Product Information

Product Name
Calcein
Brand Name
Chem Impex
Product Number
22820
CAS
1461-15-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
65079
IUPAC Name
2-7'-bis(carboxymethyl)aminomethyl-3',6'-dihydroxy-3-oxospiro2-benzofuran-1,9'-xanthene-2'-ylmethyl-(carboxymethyl)aminoacetic acid
InChI Key
DEGAKNSWVGKMLS-UHFFFAOYSA-N
SMILES
C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C(=C4)CN(CC(=O)O)CC(=O)O)O)OC5=C3C=C(C(=C5)O)CN(CC(=O)O)CC(=O)O

Description

Calcein is widely utilized in research focused on:

Fluorescent Tracers: It serves as a powerful fluorescent dye in biological studies, allowing researchers to visualize cellular processes and track the movement of cells in live organisms.

Cell Viability Assays: Commonly used in cytotoxicity testing, calcein helps determine cell health by indicating live cells through its fluorescence, providing a reliable method for assessing the effects of drugs or toxins.

Environmental Monitoring: In environmental science, calcein is employed to detect and quantify heavy metals in water samples, offering a sensitive approach for assessing water quality.

Histology and Pathology: It is utilized in tissue staining, enhancing the contrast of specific cellular components under a microscope, which aids in the diagnosis of diseases.

Biotechnology Applications: Calcein is used in various biotechnological applications, including the development of biosensors and in the study of biomolecular interactions, providing insights into complex biological systems.