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Sku CI21942_100_G
Chem Impex
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Product Information

Product Name
Podophyllotoxin
Brand Name
Chem Impex
Product Number
21942
CAS
4354-76-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
4865
IUPAC Name
5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-2benzofuro5,6-f1,3benzodioxol-8-one
InChI Key
YJGVMLPVUAXIQN-UHFFFAOYSA-N
SMILES
COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O

Description

Podophyllotoxin is widely utilized in research focused on:

Anticancer Treatments: This compound is a key ingredient in the formulation of chemotherapeutic agents, particularly for treating specific types of cancers such as testicular cancer and certain leukemias. Its ability to inhibit cell division makes it valuable in oncology.

Antiviral Applications: Podophyllotoxin has shown effectiveness against viral infections, particularly in the treatment of human papillomavirus (HPV). It is used in topical treatments to manage warts caused by HPV, providing a practical solution for patients.

Pharmaceutical Research: Researchers utilize this compound to develop new drugs and study its mechanisms of action. Its unique structure allows for modifications that can lead to more effective therapeutic agents, making it a focal point in drug discovery.

Natural Product Synthesis: As a naturally occurring compound, podophyllotoxin serves as a precursor for synthesizing other bioactive molecules. This is particularly relevant in the field of medicinal chemistry, where derivatives are explored for enhanced efficacy.

Botanical Studies: The compound is also significant in botanical research, especially in studying its effects on plant growth and development. This can lead to agricultural applications, such as developing pest-resistant crops.