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Chem Impex
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Product Information

Product Name
5-Methoxyindole-3-carboxaldehyde
Brand Name
Chem Impex
Product Number
21883
CAS
10601-19-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
82758
IUPAC Name
5-methoxy-1H-indole-3-carbaldehyde
InChI Key
TUWARWGEOHQXCO-UHFFFAOYSA-N
SMILES
COC1=CC2=C(C=C1)NC=C2C=O

Application

5-Methoxyindole-3-carboxaldehyde is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders, due to its structural similarity to serotonin.

Biochemical Research: It is used in studies investigating indole derivatives, which play significant roles in biological processes, helping researchers understand their mechanisms and potential therapeutic effects.

Fluorescent Probes: The compound can be modified to create fluorescent probes for cellular imaging, allowing scientists to visualize and track biological processes in real-time.

Natural Product Synthesis: It is involved in the synthesis of natural products that exhibit anti-cancer properties, providing researchers with tools to explore new treatments.

Material Science: The compound's unique properties make it suitable for developing functional materials, such as organic light-emitting diodes (OLEDs), enhancing the performance of electronic devices.

References

Unveiled reactivity of masked diformylmethane with enamines forming resonance-assisted hydrogen bonding leads to di-meta-substituted pyridines

Publication Name: Communications Chemistry
Publication Date: 2024-06-28
DOI: 10.1038/s42004-024-01228-w

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2023-10-30
DOI: 10.1016/j.bbrc.2023.08.050

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

Publication Name: The Journal of biological chemistry
Publication Date: 2022-08
DOI: 10.1016/j.jbc.2022.102228

Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase

Publication Name: Journal of Enzyme Inhibition and Medicinal Chemistry
Publication Date: 2022-05-05
DOI: 10.1080/14756366.2022.2070909

Triphenylphosphine/1,2-Diiodoethane-Promoted Formylation of Indoles with N,N-Dimethylformamide

Publication Name: Synlett
Publication Date: 2021-11-10
DOI: 10.1055/a-1675-1043