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Sku CI21996_100_G
Chem Impex
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Product Information

Product Name
5-Fluoroindole-2-carboxylic acid
Brand Name
Chem Impex
Product Number
21996
CAS
399-76-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
1820
IUPAC Name
5-fluoro-1H-indole-2-carboxylic acid
InChI Key
WTXBRZCVLDTWLP-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1F)C=C(N2)C(=O)O

Application

5-Fluoroindole-2-carboxylic acid is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key building block in the synthesis of various pharmaceuticals, particularly in the development of novel anti-cancer agents.

Biochemical Research: It is used in studies related to neurotransmitter systems, helping researchers understand the role of indole derivatives in brain function and mental health.

Material Science: The compound finds applications in creating advanced materials, including polymers and coatings, due to its unique chemical properties.

Agricultural Chemistry: It is explored for potential use in developing agrochemicals that enhance crop resistance to pests and diseases.

Diagnostic Tools: This chemical is being investigated for its role in the development of diagnostic agents, particularly in imaging techniques for medical applications.

References

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2023-10-30
DOI: 10.1016/j.bbrc.2023.08.050

Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2023-04-28
DOI: 10.1021/acs.jmedchem.2c01681

Target Class Profiling of Small-Molecule Methyltransferases

Publication Name: ACS Chemical Biology
Publication Date: 2023-03-28
DOI: 10.1021/acschembio.3c00124

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

Publication Name: The Journal of biological chemistry
Publication Date: 2022-08
DOI: 10.1016/j.jbc.2022.102228

Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design

Publication Name: Frontiers in Molecular Biosciences
Publication Date: 2022-05-30
DOI: 10.3389/fmolb.2022.880432