$70.10

FREE
SHIPPING

100% MONEY
BACK GUARANTEE

ONLINE
SUPPORT 24/7

Available on backorder. No lead time available. Please request a quote.
Sku CI21987_5_G
Chem Impex
Get Bulk Quote

Product Information

Product Name
6-Nitroindole
Brand Name
Chem Impex
Product Number
21987
CAS
4769-96-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
78502
IUPAC Name
6-nitro-1H-indole
InChI Key
PSWCIARYGITEOY-UHFFFAOYSA-N
SMILES
C1=CC(=CC2=C1C=CN2)N+(=O)O-

Application

6-Nitroindole is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders. Its unique structure allows for the modification of drug properties to enhance efficacy.

Fluorescent Probes: 6-Nitroindole is employed in the creation of fluorescent probes for biological imaging. These probes help researchers visualize cellular processes in real-time, providing insights into disease mechanisms.

Organic Synthesis: It acts as a versatile building block in organic synthesis, enabling chemists to develop complex molecules efficiently. This application is crucial in materials science and the development of new chemical entities.

Biochemical Research: The compound is used in studies related to enzyme inhibition and receptor binding, helping scientists understand biochemical pathways and interactions, which is vital for drug discovery.

Environmental Monitoring: 6-Nitroindole can be utilized in the detection of pollutants and environmental toxins, aiding in the development of sensors that monitor air and water quality.

References

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2023-10-30
DOI: 10.1016/j.bbrc.2023.08.050

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

Publication Name: The Journal of biological chemistry
Publication Date: 2022-08
DOI: 10.1016/j.jbc.2022.102228

Enantioselective N-Alkylation of Nitroindoles under Phase-Transfer Catalysis

Publication Name: Synthesis
Publication Date: 2019-11-26
DOI: 10.1055/s-0039-1690751

Synthesis of Nitro, Amino, and Halo Derivatives of 2-Ethyl-2-methyl-2,3-dihydro-1H-indole

Publication Name: Russian Journal of Organic Chemistry
Publication Date: 2019-10
DOI: 10.1134/s1070428019100129

Palladium-Catalyzed Dehydrogenative Aromatization of Cyclic Amines

Publication Name: Synfacts
Publication Date: 2019-07-18
DOI: 10.1055/s-0039-1690123