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Sku CI21352_100_MG
Chem Impex
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Product Information

Product Name
2-Chloro-4-nitrophenyl-a-L-fucopyranoside
Brand Name
Chem Impex
Product Number
21352
CAS
157843-41-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11359093
IUPAC Name
(2S,3S,4R,5S,6S)-2-(2-chloro-4-nitrophenoxy)-6-methyloxane-3,4,5-triol
InChI Key
QURSGHQPKUXLAD-MOBXTKCLSA-N
SMILES
CC@H1C@H(C@H(C@@H(C@@H(O1)OC2=C(C=C(C=C2)N+(=O)O-)Cl)O)O)O

Description

2-Chloro-4-nitrophenyl-a-L-fucopyranoside is widely utilized in research focused on:

Glycobiology Research: This compound serves as a valuable substrate for studying glycosylation processes, helping researchers understand carbohydrate structures and their biological functions.

Enzyme Assays: It is commonly used in enzyme assays to measure the activity of fucosidases, which are important in various biological pathways and disease mechanisms.

Drug Development: The compound can be employed in the development of new therapeutics targeting glycan-related diseases, offering potential advantages in specificity and efficacy over traditional compounds.

Diagnostic Tools: It is utilized in the creation of diagnostic assays for detecting specific glycan markers in diseases, aiding in early diagnosis and personalized medicine approaches.

Biotechnology Applications: This chemical plays a role in biotechnological processes, such as the production of glycoproteins, enhancing the yield and quality of biopharmaceuticals.

References Data Source From Pubchem

Protective Effects of Garlic and Silymarin on NDEA-Induced Rats Hepatotoxicity

Publication Name: International Journal of Biological Sciences
Publication Date: 2009-08-11
DOI: 10.7150/ijbs.5.549

Rapid kinetic rate assay of the serum alpha-L-fucosidase in patients with hepatocellular carcinoma by using a novel substrate

Publication Name: Clinica chimica acta; international journal of clinical chemistry
Publication Date: 2004-09
DOI: 10.1016/j.cccn.2004.04.007

Synthesis of 2-chloro-4-nitrophenyl alpha-L-fucopyranoside: a substrate for alpha-L-fucosidase (AFU)

Publication Name: Carbohydrate Research
Publication Date: 2003-07-22
DOI: 10.1016/s0008-6215(03)00244-1