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Sku CI21310_1_G
Chem Impex
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Product Information

Product Name
5-Chloroindole-2-carboxylic acid methyl ester
Brand Name
Chem Impex
Product Number
21310
CAS
87802-11-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
4777711
IUPAC Name
methyl 5-chloro-1H-indole-2-carboxylate
InChI Key
WGAOEHZSJWVLBY-UHFFFAOYSA-N
SMILES
COC(=O)C1=CC2=C(N1)C=CC(=C2)Cl

Application

5-Chloroindole-2-carboxylic acid methyl ester is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-inflammatory and anti-cancer agents.

Biochemical Research: It is used in studies to explore the mechanisms of enzyme inhibition and receptor binding, aiding researchers in understanding complex biological processes.

Organic Synthesis: The compound is valuable in organic chemistry for creating diverse chemical structures, allowing chemists to develop new materials and compounds with unique properties.

Agrochemical Formulations: It plays a role in the formulation of agrochemicals, contributing to the development of effective herbicides and pesticides that enhance crop yield.

Material Science: This chemical is investigated for its potential applications in creating novel polymers and coatings, offering improved durability and functionality in various industrial applications.

References

Design, synthesis, and biological evaluation of dual-target COX-2/5-LOX inhibitors for the treatment of inflammation

Publication Name: Medicinal Chemistry Research
Publication Date: 2022-12-23
DOI: 10.1007/s00044-022-02995-8

Rhodium Catalysis (Amination of Alkenes and Arenes)

Publication Name: Science of Synthesis
Publication Date: 2016

Aryl Amination with Vinyl Azides To Give Substituted Indoles

Publication Name: Science of Synthesis
Publication Date: 2015

Azides as the Nitrogen-Atom Source

Publication Name: Science of Synthesis
Publication Date: 2012

From 2-(Arylamino)aldehydes, α-(Arylamino) Ketones, or Synthons Thereof

Publication Name: Science of Synthesis
Publication Date: 2010