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Sku CI21229_250_MG
Chem Impex
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Product Information

Product Name
5-Bromo-DL-tryptophan
Brand Name
Chem Impex
Product Number
21229
CAS
6548-09-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
96735
IUPAC Name
2-amino-3-(5-bromo-1H-indol-3-yl)propanoic acid
InChI Key
KZDNJQUJBMDHJW-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1Br)C(=CN2)CC(C(=O)O)N

Description

5-Bromo-DL-tryptophan is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a valuable intermediate in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders, enhancing drug efficacy and specificity.

Biochemical Research: It is used in studies investigating serotonin pathways, helping researchers understand mood regulation and potential treatments for depression and anxiety.

Protein Engineering: 5-Bromo-DL-tryptophan is incorporated into proteins to study structure-function relationships, providing insights into enzyme mechanisms and protein interactions.

Animal Studies: This compound is employed in animal models to evaluate the effects of tryptophan derivatives on behavior and metabolism, aiding in the development of dietary supplements.

Analytical Chemistry: It is utilized as a standard in chromatographic methods, ensuring accurate quantification of tryptophan levels in various samples, which is crucial for nutritional and clinical assessments.

References Data Source From Pubchem

Indoles and the advances in their biotechnological production for industrial applications

Publication Name: Systems Microbiology and Biomanufacturing
Publication Date: 2023-12-21
DOI: 10.1007/s43393-023-00223-x

Directed evolution of a synthetic phylogeny of programmable Trp repressors

Publication Name: Nature Chemical Biology
Publication Date: 2018-02-26
DOI: 10.1038/s41589-018-0006-7

Residue-Specific Incorporation of Unnatural Amino Acids into Proteins In Vitro and In Vivo

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2013
DOI: 10.1007/978-1-62703-293-3_7

7-dimethylallyltryptophan synthase 2.5.1.80

Publication Name: Class 2–3.2 Transferases, Hydrolases
Publication Date: 2013
DOI: 10.1007/978-3-642-36240-8_68