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Sku CI19758_100_MG
Chem Impex
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Product Information

Product Name
1-Boc-1H-indazole-5-boronic acid pinacol ester
Brand Name
Chem Impex
Product Number
19758
CAS
864771-44-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
18525862
IUPAC Name
tert-butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole-1-carboxylate
InChI Key
MMXDKXUKSKMROG-UHFFFAOYSA-N
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)N(N=C3)C(=O)OC(C)(C)C

Description

1-Boc-1H-indazole-5-boronic acid pinacol ester is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of new drugs targeting cancer and neurological disorders.

Organic Synthesis: It is employed in cross-coupling reactions, enabling the formation of complex organic molecules, which is essential in the production of agrochemicals and fine chemicals.

Material Science: The compound is used in creating advanced materials, such as polymers and nanomaterials, which have applications in electronics and coatings.

Bioconjugation: It facilitates the attachment of biomolecules to surfaces or other molecules, enhancing drug delivery systems and diagnostic tools in medical research.

Research in Catalysis: This boronic acid derivative is valuable in catalytic processes, improving reaction efficiency and selectivity in synthetic chemistry.

References Data Source From Pubchem

SYNTHESIS, CRYSTAL STRUCTURE, AND A DFT STUDY OF TERT-BUTYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE

Publication Name: Journal of Structural Chemistry
Publication Date: 2021-09
DOI: 10.1134/s0022476621090043

First Identification of Boronic Species as Novel Potential Inhibitors of the Staphylococcus aureus NorA Efflux Pump

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2014-02-19
DOI: 10.1021/jm401808n