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Sku CI19514_1_G
Chem Impex
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Product Information

Product Name
Thiazole-2-carboxylic acid hydrazide
Brand Name
Chem Impex
Product Number
19514
CAS
16733-90-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
23424176
IUPAC Name
1,3-thiazole-2-carbohydrazide
InChI Key
OPJYIWMGTSMLKB-UHFFFAOYSA-N
SMILES
C1=CSC(=N1)C(=O)NN

Description

Thiazole-2-carboxylic acid hydrazide is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly in the development of anti-inflammatory and antimicrobial drugs.

Agricultural Chemistry: It is used in the formulation of agrochemicals, enhancing the effectiveness of pesticides and herbicides, which helps in improving crop yield and protecting plants from diseases.

Biochemical Research: Researchers employ this compound in studies related to enzyme inhibition and metabolic pathways, providing insights into disease mechanisms and potential therapeutic targets.

Material Science: Thiazole-2-carboxylic acid hydrazide is explored for its potential in developing novel materials, including polymers and coatings, due to its unique chemical properties.

Analytical Chemistry: It is utilized as a reagent in various analytical techniques, aiding in the detection and quantification of other compounds, which is crucial for quality control in laboratories.

References Data Source From Pubchem

A perspective on the synthetic methodologies and biological attributes of thiazole-hydrazone compounds: a medicinal chemistry-based investigation

Publication Name: Molecular Diversity
Publication Date: 2025-07-28
DOI: 10.1007/s11030-025-11306-3

Metabolic activation of N-thiazol-2-yl benzamide as glucokinase activators: Impacts of glutathione trapping on covalent binding

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2010-03-01
DOI: 10.1016/j.bmcl.2010.01.041

Synthesis and fluorescence of anthra[2,3-b]furan-5,10-dione derivatives

Publication Name: Russian Journal of Organic Chemistry
Publication Date: 2007-11
DOI: 10.1134/s1070428007110164

Synthesis of novel heterocycles from thiazolecarbohydrazides

Publication Name: Bulletin of the Russian Academy of Sciences, Division of chemical science
Publication Date: 1992-03
DOI: 10.1007/bf00863079