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Sku CI19102_5_G
Chem Impex
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Product Information

Product Name
5-Chloro-1H-indole-3-carboxylic acid methyl ester
Brand Name
Chem Impex
Product Number
19102
CAS
172595-67-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
15859771
IUPAC Name
methyl 5-chloro-1H-indole-3-carboxylate
InChI Key
QFNXAQPCYKEICY-UHFFFAOYSA-N
SMILES
COC(=O)C1=CNC2=C1C=C(C=C2)Cl

Application

5-Chloro-1H-indole-3-carboxylic acid methyl ester is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in developing drugs targeting neurological disorders.

Biochemical Research: It is used in studies investigating the mechanisms of action of indole derivatives, contributing to advancements in understanding cellular processes.

Agricultural Chemistry: The compound has potential applications in creating agrochemicals, enhancing crop protection products through its biological activity against pests.

Material Science: It can be incorporated into polymer formulations, improving the properties of materials used in coatings and adhesives.

Analytical Chemistry: This chemical is employed as a standard in analytical methods, aiding in the detection and quantification of similar indole derivatives in complex mixtures.

References

Design, synthesis, and biological evaluation of dual-target COX-2/5-LOX inhibitors for the treatment of inflammation

Publication Name: Medicinal Chemistry Research
Publication Date: 2022-12-23
DOI: 10.1007/s00044-022-02995-8

Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2021-10-11
DOI: 10.1021/acs.jmedchem.1c01077

Synthesis from Methyl 1H-Indole-3-carboxylates and 2-Bromobenzamides

Publication Name: Science of Synthesis
Publication Date: 2021