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Sku CI17727_1_G
Chem Impex
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Product Information

Product Name
1H-Indazole-5-boronic acid pinacol ester
Brand Name
Chem Impex
Product Number
17727
CAS
862723-42-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
17750469
IUPAC Name
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
InChI Key
SAGPUUKLGWNGOS-UHFFFAOYSA-N
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)NN=C3

Application

1H-Indazole-5-boronic acid pinacol ester is widely utilized in research focused on:

Medicinal Chemistry: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in developing anti-cancer agents. Its boronic acid functionality allows for selective reactions that enhance drug efficacy.

Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is vital for forming carbon-carbon bonds in complex organic molecules, making it invaluable for researchers in organic chemistry.

Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, due to its unique electronic properties and ability to form stable complexes with metals.

Agricultural Chemistry: It finds applications in the synthesis of agrochemicals, particularly herbicides and fungicides, contributing to more effective crop protection solutions.

Bioconjugation: This chemical is utilized in bioconjugation strategies to attach biomolecules to surfaces or other molecules, enhancing the delivery and targeting of therapeutic agents in biomedical applications.