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Product Information

Product Name
4-Chloro-2-phenylquinazoline
Brand Name
Chem Impex
Product Number
17270
CAS
6484-25-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
80977
IUPAC Name
4-chloro-2-phenylquinazoline
InChI Key
OBHKONRNYCDRKM-UHFFFAOYSA-N
SMILES
C1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=N2)Cl

Application

4-Chloro-2-phenylquinazoline is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly those targeting cancer and inflammatory diseases.

Biological Research: It is used in studies investigating the mechanisms of action of certain enzymes and receptors, helping researchers understand disease pathways and potential therapeutic targets.

Material Science: The compound can be incorporated into polymer matrices to enhance the properties of materials, making them suitable for advanced applications in electronics and coatings.

Agricultural Chemistry: It has potential applications in developing agrochemicals, particularly in creating herbicides or fungicides that are more effective and environmentally friendly.

Analytical Chemistry: 4-Chloro-2-phenylquinazoline is used as a standard in analytical methods, aiding in the detection and quantification of related compounds in complex mixtures.

References

Synthesis, docking, and cytotoxic activities of novel 2-aryl-4-(arylamino)quinazolines

Publication Name: Monatshefte für Chemie - Chemical Monthly
Publication Date: 2018-09-21
DOI: 10.1007/s00706-018-2270-3

Synthesis, antimicrobial and nematicidal evaluation of a new class of triazolo[4,3-c]quinazolinylthiazolidinones

Publication Name: Medicinal Chemistry Research
Publication Date: 2016-02-29
DOI: 10.1007/s00044-016-1538-6

Synthesis from 2-(Acylamino)benzonitriles

Publication Name: Science of Synthesis
Publication Date: 2015

High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors

Publication Name: Antiviral Research
Publication Date: 2011-09
DOI: 10.1016/j.antiviral.2011.06.006

Novel Palladium-Free Synthesis of a Key Quinazolinap Precursor

Publication Name: Synlett
Publication Date: 2011-01-25
DOI: 10.1055/s-0030-1259507