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Sku CI17213_1_G
Chem Impex
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Product Information

Product Name
5-Bromo-1H-indazole
Brand Name
Chem Impex
Product Number
17213
CAS
53857-57-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
761929
IUPAC Name
5-bromo-1H-indazole
InChI Key
STVHMYNPQCLUNJ-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1Br)C=NN2

Application

5-Bromo-1H-indazole is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.

Biological Research: It is used in studies investigating the mechanisms of action of certain enzymes and receptors, providing insights into cellular processes and potential therapeutic targets.

Material Science: 5-Bromo-1H-indazole is explored for its properties in creating advanced materials, including organic semiconductors and sensors, due to its unique electronic characteristics.

Agricultural Chemistry: The compound is being researched for its potential use in developing agrochemicals, particularly in creating more effective pesticides that target specific pests while minimizing environmental impact.

Diagnostic Applications: It shows promise in the development of diagnostic tools, particularly in imaging techniques that can enhance the detection of certain diseases at early stages.

References

Discovery and optimization of AAK1 inhibitors based on 1H-indazole scaffold for the potential treatment of SARS-CoV-2 infection

Publication Name: Molecular Diversity
Publication Date: 2025-04-02
DOI: 10.1007/s11030-025-11135-4

A fragment-based approach leading to the discovery of inhibitors of CK2α with a novel mechanism of action

Publication Name: RSC Medicinal Chemistry
Publication Date: 2022-11-16
DOI: 10.1039/d2md00161f

SYNTHESIS, CRYSTAL STRUCTURE, AND A DFT STUDY OF TERT-BUTYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE

Publication Name: Journal of Structural Chemistry
Publication Date: 2021-09
DOI: 10.1134/s0022476621090043

Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2016-06-15
DOI: 10.1016/j.bmcl.2016.04.073

Metalation of Pyrazoles and Indazoles

Publication Name: Metalation of Azoles and Related Five-Membered Ring Heterocycles
Publication Date: 2012
DOI: 10.1007/7081_2012_82