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Chem Impex
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Product Information

Product Name
N-Boc-3-pyrrolidinone
Brand Name
Chem Impex
Product Number
16511
CAS
101385-93-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
471360
IUPAC Name
tert-butyl 3-oxopyrrolidine-1-carboxylate
InChI Key
JSOMVCDXPUXKIC-UHFFFAOYSA-N
SMILES
CC(C)(C)OC(=O)N1CCC(=O)C1

Application

N-Boc-3-pyrrolidinone is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of new drugs targeting neurological disorders.

Organic Synthesis: It is employed in organic chemistry for creating complex molecules, offering researchers a versatile building block for synthesizing heterocycles and other functionalized compounds.

Polymer Chemistry: N-Boc-3-pyrrolidinone is used in the production of specialty polymers, enhancing properties such as flexibility and thermal stability, which are crucial in materials science.

Bioconjugation: This compound is beneficial in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other compounds, which is essential in drug delivery systems.

Analytical Chemistry: It finds application in analytical methods, aiding in the development of assays and detection techniques for various substances, thereby improving accuracy and reliability in research.

References

Design, synthesis and profiling of proteolysis-targeting chimeras (PROTACs) as CDK4/6 degraders

Publication Name: Medicinal Chemistry Research
Publication Date: 2025-06-23
DOI: 10.1007/s00044-025-03437-x

A general strategy for the amination of electron-rich and electron-poor heteroaromatics by desaturative catalysis

Publication Name: Nature Catalysis
Publication Date: 2024-04-23
DOI: 10.1038/s41929-024-01152-1

Structural and stereochemical determinants for hGAT3 inhibition: development of novel conformationally constrained and substituted analogs of (S)-isoserine

Publication Name: Medicinal Chemistry Research
Publication Date: 2023-08-16
DOI: 10.1007/s00044-023-03126-7

Oxidation Using Decatungstate

Publication Name: Science of Synthesis
Publication Date: 2022

Non-Directed β- or γ-C(sp3)–H Functionalization of Saturated Nitrogen-Containing Heterocycles

Publication Name: Synthesis
Publication Date: 2021-05-19
DOI: 10.1055/a-1483-4575