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Sku CI14286_100_MG
Chem Impex
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Product Information

Product Name
D-a-Methylproline
Brand Name
Chem Impex
Product Number
14286
CAS
63399-77-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
14463985
IUPAC Name
(2R)-2-methylpyrrolidine-2-carboxylic acid
InChI Key
LWHHAVWYGIBIEU-ZCFIWIBFSA-N
SMILES
CC@@1(CCCN1)C(=O)O

Description

D-a-Methylproline is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a valuable building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.

Peptide Synthesis: It is commonly used in the synthesis of peptides, enhancing their stability and bioactivity, which is crucial for drug formulation in the biotech industry.

Protein Engineering: D-a-Methylproline is employed in modifying proteins to improve their folding and stability, making it essential in enzyme engineering and therapeutic protein production.

Research on Chirality: This compound is significant in studies related to chirality and stereochemistry, aiding researchers in understanding the impact of molecular orientation on biological activity.

Material Science: In material science, D-a-Methylproline is used to develop new polymers with enhanced properties, contributing to advancements in materials for various applications.

References Data Source From Pubchem

The role of reactive oxygen intermediates in experimental coccidioidomycois in mice

Publication Name: BMC Microbiology
Publication Date: 2011-04-11
DOI: 10.1186/1471-2180-11-71

Bioinformatic and experimental survey of 14-3-3-binding sites

Publication Name: The Biochemical journal
Publication Date: 2010-03-15
DOI: 10.1042/bj20091834

Alkylation and Michael Addition of Enamines

Publication Name: Science of Synthesis
Publication Date: 2007

Molecular and cellular mechanisms of protective immunity to coccidioidomycosis

Publication Name: Vaccine
Publication Date: 2006-01-23
DOI: 10.1016/j.vaccine.2005.07.092