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Sku CI12881_250_G
Chem Impex
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Product Information

Product Name
O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
Brand Name
Chem Impex
Product Number
12881
CAS
148893-10-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6409673
IUPAC Name
dimethylamino-(3-oxidotriazolo4,5-bpyridin-3-ium-1-yl)methylidene-dimethylazanium hexafluorophosphate
InChI Key
FKBFHOSFPRWJNV-UHFFFAOYSA-N
SMILES
CN(C)C(=N+(C)C)N1C2=C(N=CC=C2)N+(=N1)O-.FP-(F)(F)(F)(F)F

Description

O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is widely utilized in research focused on:

Bioconjugation: This compound serves as a highly effective coupling agent in bioconjugation reactions, allowing researchers to attach biomolecules like proteins and antibodies to surfaces or other molecules, enhancing the functionality of diagnostic and therapeutic agents.

Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, providing a reliable method for creating complex peptides with high purity and yield, which is crucial in drug development and research.

Fluorescent Labeling: The chemical is employed in the labeling of biomolecules with fluorescent tags, facilitating the study of cellular processes and interactions in live cells, which is essential for biomedical research.

Pharmaceutical Development: This compound plays a significant role in the synthesis of pharmaceutical intermediates, streamlining the production of active pharmaceutical ingredients (APIs) and improving the efficiency of drug formulation processes.

Material Science: It is utilized in the development of advanced materials, including polymers and coatings, which benefit from enhanced chemical stability and performance, making it valuable in industries like electronics and automotive.

References Data Source From Pubchem

Cyclopentyl Methyl Ether (CPME)

Publication Name: Biorenewable Solvents for Organic Synthesis
Publication Date: 2024
DOI: 10.1007/978-3-031-74346-7_3

Amide-Bond Formation

Publication Name: Science of Synthesis
Publication Date: 2024

Amide-Bond-Forming Reactions

Publication Name: Science of Synthesis
Publication Date: 2024

Scalable and Efficient In Planta Biosynthesis of Sunflower Trypsin Inhibitor-1 (SFTI) Peptide Therapeutics

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2022
DOI: 10.1007/978-1-0716-1689-5_7

In-Tether Chiral Center Induced Helical Peptide Modulators Target p53-MDM2/MDMX and Inhibit Tumor Growth in Cancer Stem Cell

Publication Name: Development of In-Tether Carbon Chiral Center-Induced Helical Peptide
Publication Date: 2021
DOI: 10.1007/978-981-33-6613-8_3