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Sku CI12859_25_G
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Product Information

Product Name
Boc-glycine tert-butyl ester
Brand Name
Chem Impex
Product Number
12859
CAS
111652-20-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
4097102
IUPAC Name
tert-butyl 2-(2-methylpropan-2-yl)oxycarbonylaminoacetate
InChI Key
ZDKFMHKWZATBMR-UHFFFAOYSA-N
SMILES
CC(C)(C)OC(=O)CNC(=O)OC(C)(C)C

Description

Boc-glycine tert-butyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of protective groups that facilitate the formation of complex structures.

Drug Development: Its ability to modify amino acids makes it valuable in pharmaceutical research, particularly in designing new drug candidates with improved bioavailability and stability.

Bioconjugation: The compound is used in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other compounds, which is crucial in developing targeted therapies and diagnostics.

Research in Organic Chemistry: It serves as a versatile reagent in organic synthesis, allowing chemists to explore new reactions and develop innovative methodologies.

Protein Engineering: Boc-glycine tert-butyl ester is employed in protein engineering to create modified proteins with enhanced properties, aiding in the development of biotechnological applications.

References Data Source From Pubchem

Resolution of protected silaproline for a gram scale preparation

Publication Name: Amino Acids
Publication Date: 2011-10-15
DOI: 10.1007/s00726-011-1112-y

Radical Halogenation of Amides and Related Compounds

Publication Name: Science of Synthesis
Publication Date: 2007

Preparation of beta-nitroalanine using the Easton three-component coupling method

Publication Name: Amino Acids
Publication Date: 2006-03-20
DOI: 10.1007/s00726-006-0261-x

Glycine Cation Equivalents

Publication Name: Science of Synthesis
Publication Date: 2004