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Product Information

Product Name
N-Hydroxysulfosuccinimide sodium salt
Brand Name
Chem Impex
Product Number
12831
CAS
106627-54-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
3520574
IUPAC Name
sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate
InChI Key
RPENMORRBUTCPR-UHFFFAOYSA-M
SMILES
C1C(C(=O)N(C1=O)O)S(=O)(=O)O-.Na+

Application

N-Hydroxysulfosuccinimide sodium salt is widely utilized in research focused on:

Bioconjugation: This compound serves as an effective crosslinker for attaching proteins to surfaces or other biomolecules, enhancing the development of biosensors and diagnostic tools.

Protein Modification: It is commonly used to modify proteins for various applications, including drug delivery systems, where it helps improve stability and solubility.

Antibody Labeling: Researchers use this chemical for labeling antibodies in immunoassays, which is crucial for detecting specific proteins in complex samples.

Drug Development: In pharmaceutical research, it aids in the formulation of targeted therapies by facilitating the conjugation of drugs to carrier molecules, improving their efficacy.

Environmental Applications: It is also explored in environmental science for the development of sensors that detect pollutants, contributing to better monitoring of environmental health.

References

A novel strategy for Escherichia coli detection in raw beef in combination with click chemistry

Publication Name: npj Science of Food
Publication Date: 2025-04-24
DOI: 10.1038/s41538-025-00422-x

Crossing the Solubility Rubicon: 15-Crown-5 Facilitates the Preparation of Water-Soluble Sulfo-NHS Esters in Organic Solvents

Publication Name: Bioconjugate Chemistry
Publication Date: 2023-12-12
DOI: 10.1021/acs.bioconjchem.3c00396

Injectable and self-crosslinkable hydrogels based on collagen type II and activated chondroitin sulfate for cell delivery

Publication Name: International Journal of Biological Macromolecules
Publication Date: 2018-10-15
DOI: 10.1016/j.ijbiomac.2018.07.079

Storage stability of electrospun pure gelatin stabilized with EDC/Sulfo‐NHS

Publication Name: Biopolymers
Publication Date: 2018-09
DOI: 10.1002/bip.23232

Monoclonal antibody fragment removal mediated by mixed mode resins

Publication Name: Journal of chromatography. A
Publication Date: 2017-05-26
DOI: 10.1016/j.chroma.2017.03.063