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Sku CI11893_25_G
Chem Impex
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Product Information

Product Name
Na-Boc-L-tryptophan benzyl ester
Brand Name
Chem Impex
Product Number
11893
CAS
57229-67-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
10318477
IUPAC Name
benzyl (2S)-3-(1H-indol-3-yl)-2-(2-methylpropan-2-yl)oxycarbonylaminopropanoate
InChI Key
CEMCPAAFDOVLDW-FQEVSTJZSA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CC1=CNC2=CC=CC=C21)C(=O)OCC3=CC=CC=C3

Description

Na-Boc-L-tryptophan benzyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those involving tryptophan. Its protective Boc group allows for selective reactions, enhancing the efficiency of peptide assembly.

Drug Development: In pharmaceutical research, it is used to create novel compounds that can target specific biological pathways, particularly in the development of antidepressants and anxiolytics, leveraging the properties of tryptophan.

Bioconjugation: The benzyl ester group facilitates bioconjugation processes, making it valuable in the creation of drug delivery systems and targeted therapies, especially in cancer treatment.

Protein Engineering: Researchers utilize this compound in the modification of proteins to study their structure and function, aiding in the development of biomaterials with enhanced properties.

Analytical Chemistry: It is employed in various analytical techniques to study tryptophan-related metabolites, providing insights into metabolic pathways and potential biomarkers for diseases.

References Data Source From Pubchem

Identification of L-Tryptophan Derivatives with Potent and Selective Antagonist Activity at the NK1 Receptor

Publication Name: Journal of Medicinal Chemistry
Publication Date: 1994-04-29
DOI: 10.1021/jm00035a006

N-Acyl-L-tryptophan benzyl esters: potent substance P receptor antagonists

Publication Name: Journal of Medicinal Chemistry
Publication Date: 1993-07-09
DOI: 10.1021/jm00066a015