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Sku CI11047_1_G
Chem Impex
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Product Information

Product Name
Cyclo(-Gly-L-Phe)
Brand Name
Chem Impex
Product Number
11047
CAS
10125-07-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7076549
IUPAC Name
(3S)-3-benzylpiperazine-2,5-dione
InChI Key
UZOJHXFWJFSFAI-VIFPVBQESA-N
SMILES
C1C(=O)NC@H(C(=O)N1)CC2=CC=CC=C2

Application

Cyclo(-Gly-L-Phe) is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a building block in the synthesis of cyclic peptides, which are important for drug development due to their stability and bioactivity.

Pharmaceutical Development: It is used in the formulation of novel therapeutics, particularly in targeting specific receptors in the treatment of various diseases, including cancer and neurological disorders.

Biochemical Research: Researchers employ this compound to study protein interactions and enzyme activities, providing insights into cellular mechanisms and potential therapeutic targets.

Drug Delivery Systems: Its unique structure allows for the development of advanced drug delivery systems that enhance the bioavailability and efficacy of therapeutic agents.

Neuroscience Applications: Cyclo(-Gly-L-Phe) is explored in the field of neuroscience for its potential role in modulating neurotransmitter systems, which could lead to new treatments for mental health disorders.

References

Identification of Obscurolide-Type Metabolites and Antifungal Metabolites from the Termite-Associated Streptomyces neopeptinius BYF101

Publication Name: Journal of Natural Products
Publication Date: 2023-07-28
DOI: 10.1021/acs.jnatprod.3c00193

Zirconium Metal–Organic Framework Catalyzed Direct Amide-Bond Formation

Publication Name: Synfacts
Publication Date: 2021-09-17
DOI: 10.1055/s-0040-1720394

Intramolecular Cyclization of Amino Acid Esters

Publication Name: Science of Synthesis
Publication Date: 2021

Heterogeneous Catalysis for Amide Bond Formation

Publication Name: Synfacts
Publication Date: 2020-02-18
DOI: 10.1055/s-0039-1691671

Anti-biofilm and anti-adherence properties of novel cyclic dipeptides against oral pathogens

Publication Name: Bioorganic & Medicinal Chemistry
Publication Date: 2019-06-15
DOI: 10.1016/j.bmc.2018.11.042