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Product Information

Product Name
2-Methyl-L-phenylalanine
Brand Name
Chem Impex
Product Number
07426
CAS
80126-53-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2761493
IUPAC Name
(2S)-2-amino-3-(2-methylphenyl)propanoic acid
InChI Key
NHBKDLSKDKUGSB-VIFPVBQESA-N
SMILES
CC1=CC=CC=C1CC@@H(C(=O)O)N

Application

2-Methyl-L-phenylalanine is widely utilized in research focused on:

Pharmaceutical Development: This compound is explored for its potential in developing new drugs, particularly in the treatment of neurological disorders, due to its structural similarity to amino acids that influence neurotransmitter activity.

Protein Engineering: Researchers use it to create modified proteins with enhanced properties, as it can be incorporated into peptides to study structure-function relationships in proteins.

Biotechnology: In the field of synthetic biology, it serves as a building block for creating novel biomolecules, enabling the engineering of microorganisms for bioproduction.

Food Industry: Its unique flavor profile makes it a candidate for flavor enhancement in food products, appealing to manufacturers looking for natural flavoring agents.

Research in Metabolic Pathways: Scientists investigate its role in metabolic processes, helping to understand amino acid metabolism and its implications for human health.

References

LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2016-06-01
DOI: 10.1016/j.bmcl.2016.04.023

Preparative separation and identification of derivatized beta-methylphenylalanine enantiomers by chiral SFC, HPLC and NMR for development of new peptide ligand mimetics in drug discovery

Publication Name: Journal of Pharmaceutical and Biomedical Analysis
Publication Date: 2006-03-03
DOI: 10.1016/j.jpba.2005.08.034

Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2006-03-01
DOI: 10.1016/j.bmcl.2005.11.052

Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2005-05-16
DOI: 10.1016/j.bmcl.2005.03.055

Separation of Enantiomers of Non-Protein Amino Acids by High-Performance Liquid Chromatography on a Chiral Ligand-Exchange Column

Publication Name: Chromatographia
Publication Date: 2004-06-18
DOI: 10.1365/s10337-004-0298-5