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Sku CI07382_1_G
Chem Impex
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Product Information

Product Name
3-Trifluoromethyl-L-phenylalanine
Brand Name
Chem Impex
Product Number
07382
CAS
14464-68-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2777600
IUPAC Name
(2S)-2-amino-3-3-(trifluoromethyl)phenylpropanoic acid
InChI Key
BURBNIPKSRJAIQ-QMMMGPOBSA-N
SMILES
C1=CC(=CC(=C1)C(F)(F)F)CC@@H(C(=O)O)N

Application

3-Trifluoromethyl-L-phenylalanine is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a building block in the synthesis of novel pharmaceuticals, particularly in the design of drugs targeting neurological disorders due to its unique electronic properties.

Peptide Synthesis: It is used in peptide synthesis to introduce trifluoromethyl groups, enhancing the stability and bioactivity of peptides, which is crucial in drug formulation.

Biochemical Research: Researchers leverage its properties to study protein interactions and enzyme activities, providing insights into metabolic pathways and disease mechanisms.

Material Science: The compound is explored in creating advanced materials with specific thermal and electrical properties, beneficial in electronics and nanotechnology.

Fluorinated Compounds Research: It plays a significant role in the development of fluorinated compounds, which are known for their unique characteristics in pharmaceuticals and agrochemicals, offering advantages over non-fluorinated analogs.

References

Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2018-07-26
DOI: 10.1021/acs.jmedchem.8b01007